At AstraZeneca, we turn ideas into life changing medicines. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality.
We’re
passionate about the potential of science to address the unmet needs of patients around the world. We commit to those areas where we believe we can really change the course of medicine and bring big
new ideas
to life.
Are you ready to work on one of the most exciting
Oncology
pipelines in industry?
AstraZeneca’s vision in Oncology is to push the boundaries of science to change the practice of medicine, transform the lives of patients living with cancer, and to
ultimately eliminate
cancer as a cause of death.
We are
seeking
a
highly motivated
Senior Scientist
with deep scientific and technical
expertise
spanning both adaptive
and innate
immune cell biology
with
a track record
of scientific excellence to join
Immune Cell Engagers Discovery
team
in Cambridge, UK
for
a
12-month
period . As a Senior Scientist ,
you will be a key member of a team focused on supporting immune-oncology projects through the drug discovery process. You will bring your theoretical and practical
expertise
in immunology to
establish
assay systems and deliver datasets that will have direct impact on
immune-oncology research projects.
Main Duties and Responsibilities
Working in this laboratory-based position within the Immun e Cell Engagers D iscovery
group ,
you will develop, design, conduct and analyse
in - vitro
and/or
ex - vivo
experiments to assess the function of our candidate drugs and help
us
to dissect the mechanism of action of novel therapeutics targeting the immune system for cancer therapy. You will also review emerging literature and internal data to help in
identifying
new potential targets and contribute to target validation activities.
A strong foundation
in immunology / immuno-oncology, and
an in- depth
Information from public records, not immigration advice.
The salary is an estimate from national earnings data, not the employer's figure.
Why
In favour: Licensed for Skilled Worker
AstraZeneca UK Limited is on the register with an active Skilled Worker route (Worker (A rating)).
Home Office register of licensed sponsors
In favour: Occupation is eligible for Skilled Worker
Occupation code 2113 (Biochemists and biomedical scientists) is eligible for the Skilled Worker route on the rules in force from 11 Nov 2025.
Immigration Rules Appendix Skilled Occupations
Against: Estimated salary is below the going rate
No salary is stated, so this uses an estimate of £43,790 from ASHE estimate (low end of the senior band) (1 Apr 2025). It falls £2,110 short of the going rate for occupation code 2113 of £45,900. Because that salary is estimated rather than stated, this rule counts half.
Immigration Rules Appendix Skilled Occupations
In favour: A rating on the licence
The register shows “Worker (A rating)”, the rating a licence carries when it is not on an action plan.
Home Office register of licensed sponsors
In favour: A larger employer
Companies House records accounts of category “FULL”, filed by companies above the small-company thresholds.
Companies House
Not established: The advert says nothing about sponsorship
We searched the advert for the usual wording in both directions and found none of it.
The advert itself
Home Office register of licensed sponsors snapshot
gene expression analysis and stable cell line generation.
Working e xperience with immune cell
assays
and/or
characterization is highly desirable.
Strong interpersonal, influencing, negotiating and collaboration skills together with evidence of having used these
skills
to support problem solving and
in
deliver ing the
projects in
a collaborative environment.
Depth of understanding and
strong
enthusiasm for immunology and immuno-oncology .
Proven
track record
of
scientific accomplishments ,
as
evident
from publication s/patents.
Data processing, statistical
analysis,
and interpretation.
Experience
in
preparing written scientific reports ( e.g.,
manuscripts) and oral presentations ( e.g.,
slides, posters).
Ability to record protocols and experiments
in a timely manner
and
maintain
an excellent electronic
notebook
( eLNB ) .
Desirable Requirements
We encourage applications from candidates who have
experience in the evaluation of immune
cell
function s
and
in
developing
and deploying
complex immunological assays
to understand the MOA of novel therapeutics .
Expertise
in field s
of T -cell engagers,
T cell exhaustion, tumour myeloid and/or NK biology .
Experience
in
visualizing/quanti fying
high content multi-parameter flow
cytometry
data
/ transcriptomic datasets .
Candidates who can
demonstrate
proficiency
in
leveraging
AI technologies, including machine learning, data analysis, and algorithm development to enhance research outcomes, alongside strong
problem solving
skills, to enable integration of these tools into scientific workflows are strongly preferred.
Prior experience with spectral flow cytometry .
Working e xperience with 3D
cell culture .
Experience
in
working with patient-derived tumours/TILs
Knowledge of the drug discovery process .
When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. Why AstraZeneca: Here, scientific rigor meets real-world impact. You will collaborate with inquisitive colleagues, academic partners and biotech innovators to tackle complex disease biology, supported by leading technologies in data science and AI. We combine ambition with kindness, encouraging bold ideas while learning fast from both successes and setbacks. By contributing your experiments and insights, you help convert biology into therapies at speed—advancing a pipeline designed to reach more patients, across more indications, with purpose and care.
Call to Action: Take this chance to amplify your science and see your work shape the next wave of medicines—join us to turn high-quality experiments into life-changing progress for patients. Date Posted 07-set.-2026 Closing Date 14-set.-2026 Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.
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